The Hampton Inn Cape Girardeau hotel is located off Interstate 55 and four miles west of downtown Cape Girardeau, Missouri. Area attractions near our hotel include shopping centers, historical sites, and more.The hotel offers a business center and a fitness center. The hotel amenities also include On-the-Run Breakfast Bag™, On-the -House™ hot breakfast, complimentary high-speed Internet access, and meeting rooms. Other amenities include laundry service and room service.The hotel features 81 rooms. Coffeemakers, irons, hairdryers, work desks, complimentary high-speed Internet access, and cable TV are standard in every room.