Enjoy your stay at a state of the art hotel in Clemson with cosmic, Clemson decor. Our Holiday Inn Express & Suites Clemson hotel is located at 1381 Tiger Blvd (HWY 123), nearby Clemson University, home of the Clemson Tigers.The Holiday Inn Express Clemson hotel is located nearby Seneca, Anderson, Central, Easley, Liberty, Six Miles, Walhalla, Pickens and Westminster. Nearby attractions include Southern Wesleyan University, SC Botanical Garden, Brooks Center, Garrison Arena, Death Valley and Little John Coliseum. Business travelers enjoy our location and corporate amenities, too. This Clemson Hotel is nearby Duke Power, Michelin, Milliken, Safe Mark Corporation, Pickens Corporate Park, BASF, Madren Conference Center and Clemson University ICAR. Our Clemson hotel has a 24 hour business center with copy and fax services, as well as a 1,300 sq ft meeting room, which can accommodate up to 85 people. We offer great amenities to please leisure and business travelers, such as a free, hot breakfast bar with outdoor deck seating, a heated, indoor pool, a sun deck, a well-equipped fitness center and free wired and Wi-Fi Internet access. Stay at one of the finest hotels in Clemson and enjoy our cosmic, contemporary lobby and a friendly staff waiting to show you real Southern hospitality.